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OCR: ecretin Since surgical therapy of large prolactin lactin pituitary tumours normalises serum pr venty per igh levels or gonadal function in less than t cent of patients, particularly those with er prolactin levels, there is a need for anot nes of approach to the problem. Three major l ay help in evidence suggest that medical therapy n the treatment of these large tumours: as pressing . Visual field defects due to prolactinon on the optic chiasm have improved wit bromocriptine therapy alone. own, by . Dopamine agonist therapy has been s) he size of neuroradiologic evaluations, to reduce prolactinomas, and the · Bromocriptine reduces DNA turnove he rat. mitotic index in the in situ pituitary of